New alternatives for Chagas' disease control
نویسندگان
چکیده
منابع مشابه
Control of Chagas' disease vectors.
Most Latin American countries are making dramatic progress in controlling Chagas disease, through a series of national and international initiatives focusing on elimination of domestic populations of Triatominae, improved screening of blood donors, and clinical support and treatment of persons infected with Trypanosoma cruzi. Some countries, particularly Uruguay, Chile and Brazil, are sufficien...
متن کاملChagas disease vector control and Taylor's law
BACKGROUND Large spatial and temporal fluctuations in the population density of living organisms have profound consequences for biodiversity conservation, food production, pest control and disease control, especially vector-borne disease control. Chagas disease vector control based on insecticide spraying could benefit from improved concepts and methods to deal with spatial variations in vector...
متن کاملFexinidazole: A Potential New Drug Candidate for Chagas Disease
BACKGROUND New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations, including failure to uniformly achieve parasitological cure or prevent the chronic phase of CD, and safety and tolerability concerns. Fexinidazole, a 2-subsituted 5-nitroimidazole drug candidate rediscovered following extensive compound mini...
متن کامل[Chagas disease].
Chagas disease (human American trypanosomiasis) is a zoonose caused by the protozoan Trypanosoma cruzi. Vectors are Triatoma spp. insects. T. cruzi can also be transmitted by blood transfusion, organ transplantation, and transplacentally. Infection is generally acquired during infancy. The acute infection is rarely symptomatic and is followed by a chronic phase. Chronic infected people are asym...
متن کاملChagas' disease.
Chagas' disease is one of the most important public health problems in South America and Mexico. Migrations from rural areas into urban zones have contributed to the spread of the disease. The main targets of the disease within the body are the heart, the alimentary tract, and the nervous system. In the acute phase of the disease, the parasite responsible for the disease can be identified in th...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1984
ISSN: 0074-0276
DOI: 10.1590/s0074-02761984000500022